Tinie Tempah as King Louis XV for the Sunday Times Style magazine’s fashion royalty issue

Hip hop’s most stylish man, Tinie Tempah, got given a King Louis XV makeover for the issue

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Vision Loss, Depression May Be Linked, Study Finds

Title: Vision Loss, Depression May Be Linked, Study Finds
Category: Health News
Created: 3/7/2013 4:36:00 PM
Last Editorial Review: 3/8/2013 12:00:00 AM

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Cholesterol Levels May Vary By Season

Brazilian study doesn't necessarily mean that heart attack or stroke risk rises in winter

By Steven Reinberg

HealthDay Reporter

THURSDAY, March 7 (HealthDay News) -- Cholesterol levels increase with winter's arrival and drop again as warmer weather returns, a new study by Brazilian researchers suggests.

"In the winter, people should be careful with their cholesterol levels," said lead researcher Dr. Filipe Moura, a doctoral student at the State University of Campinas.

Whether these changes in cholesterol are putting patients at risk for heart attacks or stroke isn't clear, Moura said. It's a complex picture and these changes might have a role, but there are many other factors, he added.

There are several possible reasons cholesterol varies by season, Moura said, including changes in diet, exercise and exposure to the sun.

"In the winter, people consume more calories and eat fattier foods, which could have an effect on their bad cholesterol," he said. "Also, it's common for people to exercise less during the winter and stay in more."

People also get less sun in the winter, so they get less vitamin D, which can have an effect on cholesterol, Moura said. He also noted that during the winter people are prone to colds and the flu, which can effect cholesterol levels.

The study findings were scheduled to be presented Saturday at the annual meeting of the American College of Cardiology in San Francisco.

Moura's team collected data on more than 227,000 people who had their cholesterol checked in primary-care centers in the Brazilian city of Campinas between 2008 and 2010.

The researchers found that during the winter, low-density lipoprotein (LDL), or "bad" cholesterol, rose an average of 7 milligrams per deciliter compared to the summer, which is about an 8 percent increase during the cold months. During the summer, levels of high-density lipoprotein (HDL), the "good" cholesterol, rose about 9 percent, but so did levels of fats in the blood called triglycerides, which rose about 5 percent, the researchers found.

This is different than what other studies have found, Moura said. A possible explanation is Campinas's climate. The city's elevation is roughly 1,800 to 2,500 feet above sea level, and the winters are mild and dry.

Moura said these changes may be even more extreme in the United States, Europe or other areas that have bigger climate changes between winter and summer.

He next plans to look at patients with heart disease to see whether the seasonal change in cholesterol results in more heart attacks.

What these findings mean for patients isn't clear, said Dr. Gregg Fonarow, a spokesman for the American Heart Association and a professor of cardiology at the University of California, Los Angeles.

"This study suggests there may be modest seasonal variation ... with higher LDL levels in winter months compared to summer, but further studies are needed to confirm these findings and whether there is any meaningful impact on cardiovascular risk," Fonarow said.

Because this study was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

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Tips on Coping With Daylight Saving Time

Title: Tips on Coping With Daylight Saving Time
Category: Health News
Created: 3/8/2013 10:35:00 AM
Last Editorial Review: 3/8/2013 12:00:00 AM

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High-Fiber Diet Helps Heart Too, Expert Says

Title: High-Fiber Diet Helps Heart Too, Expert Says
Category: Health News
Created: 3/2/2013 10:35:00 AM
Last Editorial Review: 3/4/2013 12:00:00 AM

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Sophia Hamilton, Textiles Student

Browse through the street style and fashion photoblog online at Glamour.com. Check out the latest fashion, as worn by you!

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Shared Genes May Link ADHD, Autism and Depression

By Steven Reinberg

HealthDay Reporter

WEDNESDAY, Feb. 27 (HealthDay News) -- Autism, attention-deficit/hyperactivity disorder (ADHD), major depression, bipolar disorder and schizophrenia may all share common genetic risk factors, a new study says.

In this largest study of its kind, researchers spotted gene variations governing brain function that may raise the risk for these often devastating mental woes. In the future, these gene variants might become key targets for prevention or treatment, the scientists said.

"This study, for the first time, shows that there are specific genetic variants that influence a range of childhood and adult-onset psychiatric disorders that we think of as clinically different," said lead researcher Dr. Jordan Smoller, a professor of psychiatry at Harvard Medical School in Boston.

"We also found that there was significant overlap in the genetic components of several disorders, especially schizophrenia with bipolar disorder and depression, and to a lesser extent autism with schizophrenia and bipolar disorder," he said.

The researchers don't yet understand exactly how these variants are involved in the disorders, he noted. "This is the first clue that specific genes and pathways may cause a broader susceptibility to a number of disorders. Now the important work will be to figure out how this actually happens," said Smoller, who is also associate vice chair of the department of psychiatry at Massachusetts General Hospital.

Dr. Alessandro Serretti, from the Psychiatry Institute at the University of Bologna in Italy, wrote an accompanying journal editorial on the study. He believes that "we are now able to understand what are the pathways to [these] psychiatric disorders."

There are potential clinical applications, both in the classification of disorders, predicting who's most at risk, and perhaps new and better drug therapies, Serretti said. However, there's no immediate clinical application for these findings, he added.

The report was published Feb. 28 in the online edition of The Lancet.

To look for common genetic markers, called nucleotide polymorphisms, that might be risk factors for the five disorders, the Psychiatric Genomics Consortium scanned the genes of more than 33,000 people suffering from these disorders and nearly 28,000 people without such issues. This is the largest study of the genetics of psychiatric illness yet conducted, the researchers said.

Smoller's group found four gene areas that all overlapped with the five disorders, two of which regulate calcium balance in the brain.

These overlapping gene variants appear to increase the risk for bipolar disorder, major depressive disorder and schizophrenia in adults, the researchers said.

Further analysis found that genes governing calcium channel activity in the brain might also be important in the development of all five disorders, autism and ADHD included.

Smoller noted these genetic risk factors may only account for a very small part of the risk driving these disorders, and just how big a share they account for isn't yet known.

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Q&A: Breast Cancer in Young Women

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