Wednesday, February 27, 2013

Kate Moss’ fuss-free down-do


Kate Moss wears her hair in a long straight down-do style – Hair Do's & Don'ts brought to you by Glamour.com. Visit Glamour.com for the latest dos and don'ts for hairstyles, with celebrity photos.

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Damian Lewis at a party in London


Homeland hunk (we totally went there) Damian Lewis struck his best hands-in-pockets pose for photographers at a party in London last night.

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Antidepressants Celexa, Lexapro Tied to Irregular Heartbeat: Study

But the occurrence is rare, and alternatives

TUESDAY, Jan. 29 (HealthDay News) -- People taking certain antidepressants, including Celexa and Lexapro, may have a slightly increased risk of developing an abnormal heart beat.

Researchers say the drugs, which are in a class of medications called selective serotonin reuptake inhibitors (SSRIs), may extend the length of electrical activity in the heart, called a QT interval. A long QT interval is an indicator of abnormal heart rhythms.

"For people who are taking higher doses of citalopram (Celexa) or escitalopram (Lexapro), they should discuss these doses with their doctors," said lead researcher Dr. Roy Perlis, director of the Center for Experimental Drugs and Diagnostics in the psychiatry department at Massachusetts General Hospital in Boston.

"They should absolutely not just stop their medicine," he added.

QT interval is just one indicator of cardiac risk, so there are many other factors to consider in choosing a depression treatment, Perlis said. "It's important to know that there are other medicines which appear to be safe in terms of effects on heart rhythm," he added.

The report was published in the Jan. 29 online edition of the journal BMJ.

Doctors use an electrocardiogram (ECG) to measure the QT interval. The interval varies with heart rate, lengthening when the heart beats slower and shortening when the heart beats faster.

The normal QT interval for men is less than 420 milliseconds and for women it is less than 440 milliseconds. When the timing gets longer, the risk for abnormal heart rhythms increases, the researchers noted.

The U.S. Food and Drug Administration warned recently that Celexa and drugs like it could cause this problem.

To shed light on the matter, Perlis' team collected data on more than 38,000 adults who had an ECG after using antidepressants or methadone between February 1990 and August 2011. They found patients taking Celexa, Lexapro, Elavil (amitriptyline) and methadone had a small but significantly longer QT interval. This effect grew as dosage increased, they noted.

Nearly one in five patients taking these drugs had longer QT intervals, the study found. Whether this effect is clinically significant, however, isn't known.

"For people who need to take antidepressant doses higher than 40 milligrams of citalopram, there are a number of safe alternatives," Perlis said.

Other antidepressants were not associated with longer QT intervals. In one case, the opposite occurred.

"To our surprise, we also found that another antidepressant, bupropion (Wellbutrin, Zyban), actually shortens QT interval, though we don't know whether this is beneficial or just another indication that it is safe from a cardiac perspective," he said.

In the study, the researchers took other risk factors into account, such as age, race, sex, history of depression, heart attack, high blood pressure, heart rhythm problems and pre-existing conditions. They included methadone because it is also known to cause a longer QT interval.


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Amber Atherton at a Casio launch party in London


Amber Atherton wears a striped knit and leather skirt by AllSaints at a Casio launch party in London - vote on celebrity fashion, style and red carpet looks in GLAMOUR.COM’s Dos and Don’ts

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David Beckham trains with Arsenal FC

David Beckham trains with Arsenal FC
After filming for an advert in Marbella yesterday, he’s back in the UK and training with Arsenal FC.

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Gwen Stefani on the street in LA


Gwen Stefani wears a blazer with exaggerated shoulders and cargo pants on the street in LA - vote on celebrity fashion, style and red carpet looks in GLAMOUR.COM’s Dos and Don’ts

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8 Healthy Facts About Pineapple

Our guide to this thorny (but sweet) fruit -- plus a delicious shrimp and pineapple kebab recipe!By Ana Ferrer
WebMD Magazine - Feature

Pineapple Discovery

In 1493, explorer Christopher Columbus found pineapples on Guadeloupe Island in the Caribbean. The fruit is also native to southern Brazil and Paraguay.

Pineapples in Colonial America

American colonists regarded pineapples as a luxurious treat because of their rarity and cost.

Pineapple Anatomy

A pineapple is the result of many flowers whose fruitlets have joined around the core.

Pineapple Nutrition

Pineapples contain bromelain, an enzyme that may help arthritis pain by reducing inflammation. They are also a good source of vitamin C, which helps strengthen your immune system.

Pineapples in Hawaii

Historically, Hawaii was the world's largest pineapple producer and source for U.S. pineapples. Some of the largest pineapple crops were in Hawaii. Today the largest producers include the Philippines, Brazil, and Costa Rica. 

Pineapple Selection

Pass over sour-smelling or bruised pineapples. Fruit from Hawaii or Central America tends to be freshest.

Pineapple Care

To make your pineapple softer and juicier, keep it at room temperature for one or two days before cutting.

Pineapple Calories

One cup of pineapple has 70 to 85 calories.

Hawaiian Grilled Pineapple Shrimp Kebabs

Makes 4 servings

Ingredients

3 cloves garlic, minced

1 tsp fresh (or bottled) minced ginger

1 tbsp cider or rice vinegar

1 tbsp low-sodium soy sauce

1 tsp five-spice powder (optional)

1 tsp dark sesame oil

1 tsp honey

1/2 cup pineapple juice

1 lb large shrimp, peeled (can substitute top-sirloin beef)

2 large sweet red peppers, cut into bite-sized pieces

12 pearl onions, fresh (or frozen) and peeled

1 8-oz package whole mushrooms, cleaned

2 cups fresh pineapple chunks (or canned in fruit juice, no sugar added)

vegetable cooking spray

Directions

1. Combine first eight ingredients in zip-top plastic bag, then add shrimp. Marinate in refrigerator 30 minutes.

2. Remove shrimp from marinade. Place marinade in a small saucepan, bring to a boil, and set aside for basting.

3. Preheat grill to medium high. Spray with cooking spray. Thread vegetables, pineapple, and shrimp onto metal skewers. (If using wooden skewers, soak in water 30 minutes to prevent burning on the grill.) 

4. Place kebabs on grill, covered, over medium-high heat for 3 to 5 minutes per side until done, basting with reserved marinade. 

5. Drizzle remaining marinade over kebabs. Serve with brown rice.

Per serving: 251 calories, 27 g protein, 29 g carbohydrate, 4 g fat (1 g saturated fat), 170 mg cholesterol, 4 g fiber, 19 g sugar, 311 mg sodium. Calories from fat: 13%.

Find more articles, browse back issues, and read the current issue of  WebMD the Magazine.


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Gerard Butler at the International Fine Watchmakers’ Fair


Gerard Butler posed for a portrait at the International Fine Watchmakers’ Fair in Geneva yesterday. Clearly a watch fan.

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