Posts
Jennifer Lawrence wears a black Prabal Gurung gown at the Critics’ Choice Movie Awards- vote on celebrity fashion, style and red carpet looks in GLAMOUR.COM’s Dos and Don’tsContinue reading...
Tuesday, January 22, 2013
Jennifer Lawrence at the Critics' Choice Movie Awards
Jennifer Lawrence wears a black Prabal Gurung gown at the Critics’ Choice Movie Awards- vote on celebrity fashion, style and red carpet looks in GLAMOUR.COM’s Dos and Don’tsContinue reading...
Pap Test to Detect Ovarian, Endometrial Cancers?
Jan. 9, 2013 -- A new test for ovarian and endometrial cancers looks at cervical fluid obtained during a routine Pap test to detect genetic mutations linked with the cancers.
Although the research is in early stages, the test did well in detecting these cancers, says researcher Yuxuan Wang, a graduate student at the Ludwig Center for Cancer Genetics and Therapeutics at the Johns Hopkins University's Kimmel Cancer Center in Baltimore.If ongoing research bears out, the new test could someday become a routine screening test, much like the Pap test is for cervical cancer, she says.
"This would not add anything to the current [Pap] procedure," Wang says. "All we do is take part of the sample for DNA testing.''
The cervical fluid collected during a Pap smear contains normal DNA and, if a person has cancer, DNA from those cancer cells.
The researchers used genomic sequencing to pick out the cancerous DNA from the normal DNA.
The study is published in Science Translational Medicine.
Widespread use of the Pap test has reduced deaths from cervical cancer and increased early detection. But finding reliable screening tests for ovarian and endometrial cancers has been elusive.
More than 69,000 U.S. women were expected to get a diagnosis of either ovarian or endometrial cancer in 2012.
If endometrial cancer is suspected, a doctor may order a transvaginal ultrasound. If ovarian cancer is suspected, a doctor may order a blood test that looks for CA-125, a protein found at high levels in some ovarian cancer patients.
Neither test is as reliable as a screening test, the researchers say. The U.S. Preventive Services Task Force and the American Cancer Society do not recommend general routine screening for endometrial or ovarian cancer.
During a Pap test, cells collected from the cervix are examined for signs of cancer. The DNA in the Pap sample may also be examined for human papillomavirus (HPV), which causes cervical cancer.
The cervical fluid collected during the Pap test can also contain cells shed from the ovaries or the uterine lining (the endometrium).
Cancer cells from either the ovaries or endometrium could also be present in the fluid, the researchers say.
In the new study, the researchers determined the most common genetic mutations found in ovarian and endometrial cancers.
"We ended up with 12 genes," Wang says. The test they developed, called the PapGene test, looks for mutations on those 12 genes.
They searched for the mutations in 24 endometrial cancer tissue samples and 22 ovarian cancer tissue samples.
Mutations were found in all 46 samples.
They looked at the Pap test to see if the same mutations were found as they found in the tissue samples.
Daniel Radcliffe spotted leaving The Ivy in London
They’ll be no Golden Globes shenanigans for Daniel Radcliffe this weekend. We spotted the Harry Potter actor leaving The Ivy restaurant in London yesterday, where he dined with pals.Continue reading...
Emma Stone Interview
Taylor Lautner and Sara Hicks leave The Staples centre in Los Angeles
We snapped Taylor Lautner driving out of the Staples centre with his high school sweetheart, cheerleader Sara Hicks, after watching an LA Clippers basketball game yesterday. Continue reading...
Amanda Seyfried at the Critics Choice Movie Awards
Amanda Seyfried wears a blue lace dress by Marios Schwab at the Critics’ Choice Movie Awards- vote on celebrity fashion, style and red carpet looks in GLAMOUR.COM’s Dos and Don’tsContinue reading...
Anne Hathaway at the Critics' Choice Movie Awards
Anne Hathaway wears a gold embellished gown by Oscar de la Renta at the Critics’ Choice Movie Awards- vote on celebrity fashion, style and red carpet looks in GLAMOUR.COM’s Dos and Don’tsContinue reading...
Leslie Mann at the Critics' Choice Movie Awards
Leslie Mann wears a pink dress by Honor at the Critics’ Choice Movie Awards- vote on celebrity fashion, style and red carpet looks in GLAMOUR.COM’s Dos and Don’tsContinue reading...
Naomi Watts at the Critics’ Choice Movie Awards
Naomi Watts wears black Emilio Pucci dress at the Critics’ Choice Movie Awards - Check out Dos and Don'ts rating celebrity style online at Glamour.com. Visit Glamour.com for the low down on fashion trends and celebrity gossip. Continue reading...
Subscribe to:
Posts (Atom)